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"This experience has compelling meaning and a spiritual element that is strongly preserved over the long term," said Roland Griffith of the Johns Hopkins University School of Medicine in Baltimore, the lead author of the study.
In the original study, only a single dose was given to 36 patients, but at the time of follow-up, they were reported to still consider the experience to be a valuable sequela.
A series of new trials of psilocybin are currently being planned or underway in the United States, hoping to reduce cancer-related risks with a single dose that will give patients lasting and positive results.
Changes in progress
The latest study, published in the Journal of Psychopharmacology 1, follows the 2006 experiment, where Griffiths and colleagues administer high doses of psilocybin to 36 "mental" volunteers who have never used hallucinogens. I did 2. Participants were encouraged to turn their attention inward during the experience, and two months later, many reported continuous and positive changes in their lives.
"Unification of existence and realization of the theory of relativity of ordinary consciousness ... I had a glimpse of this before, but it was profound and persistent," read a comment on one participant's experience. Please. Another comment: "It was so wonderful to be with God that words cannot explain the experience.
Of the 22 original participants who had a "complete" mystical experience as defined in the Pahnke-Richards Mystical Experience Questionnaire, all met the same criteria except after 14 months.
Most volunteers with mystical experiences continue to support the same positive changes in attitudes, altruistic behaviors, and moods, says Griffith.
After 14 months, 67% of participants rated this treatment as one of the five most psychologically important moments in life, and 17% rated it as the most psychologically deep experience. In addition, 64% of subjects reported increased well-being or life satisfaction.
Griffith says that in psychopharmacology, it is unusual for a single dose to have a long-lasting positive effect.
However, this survey is based on a retrospective survey and a sample of people who already have a spiritual spirit. Griffith admits that the data is biased, but says he looks forward to moving on to more active prospective studies. "This opens up many scientific questions and therapeutic applications."
However, not everyone agrees thatpsychedelicsare in medicine. While Griffith Edwards, an emeritus professor of addiction research and co-founder of the National Center for Poisoning, respects the authors of the study and their conclusions, such drugs can have serious and beneficial effects. Don't forget that. People can have self-destructive and suicidal thoughts, as well as mystical experiences, he says. Edwards adds that he is concerned that this is being seen as a trigger for a new campaign for healthcare professionals. There are other ways to help people, he says.